22-250 Remington Ammo
Shop in-stock 22-250 Remington ammunition in bulk with next-business-day shipping. Federal soft point, Federal Varmint & Predator, and Hornady V-MAX varmint loads in 200-round cases. Read more about 22-250 ammo.
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Up to $60 Rebate
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22-250 Rem – 50 gr JHP – Federal Varmint & Predator (AE22250G) – 200 Rounds
$304.00$1.52 per round Add to cart -
22-250 Rem – 55 gr V-MAX – Hornady Varmint Express (8337) – 200 Rounds
$314.00$1.57 per round Add to cart
Overview of 22-250 Remington Ammo
22-250 Remington is one of the fastest and flattest-shooting varmint cartridges ever made. It fires a .224-inch bullet, usually 40 to 55 grains, at 3,600 to 4,000 fps or more. That speed gives a very flat trajectory out to 400 yards and explosive results on prairie dogs, groundhogs, coyotes, and foxes.
22-250 uses the same diameter bullet as .223 Remington but carries far more powder, so it shoots flatter and drifts less in the wind. It runs in bolt-action and single-shot rifles rather than AR-15s. For an AR-15 varmint option, see our .223 Remington ammo.
22-250 Brands We Carry
- Federal 22-250 Ammo: Power-Shok 55gr soft point for coyotes and predators, and American Eagle Varmint & Predator 50gr JHP for high-volume varmint shooting.
- Hornady 22-250 Ammo: Varmint Express 55gr V-MAX, a polymer-tipped bullet built for rapid expansion.
Best 22-250 Ammo for Specific Uses
| Use Case | Top Pick | Also Consider |
|---|---|---|
| Prairie Dogs / Groundhogs | Federal Varmint & Predator 50gr JHP | Hornady Varmint Express 55gr V-MAX |
| Long-Range Varmints | Hornady Varmint Express 55gr V-MAX | Federal Varmint & Predator 50gr JHP |
| Coyotes / Predators | Federal Power-Shok 55gr SP | Hornady Varmint Express 55gr V-MAX |
Why Buy 22-250 Ammo from BulkMunitions?
- In stock and ready to ship. We only list ammunition that is physically in our warehouse. No backorders.
- Next-business-day shipping from our Knoxville, TN warehouse on orders placed before our daily cutoff.
- Case pricing for varmint season. 200-round cases cost less per round than 20-round boxes and cover a full day in a prairie dog town.
- We tithe 10% of profits to Christian-based, 2A-supporting organizations every quarter, and our customers vote on where it goes.
Frequently Asked Questions
Is 22-250 good for deer hunting?
22-250 can take deer with a heavy, controlled-expansion bullet and careful shot placement, but most hunters prefer a larger cartridge like .243 Winchester or 6.5 Creedmoor for deer. Some states set minimum caliber requirements for deer, so check your state's regulations before hunting.
What is the difference between 22-250 and .223?
Both fire .224-inch bullets, but 22-250 uses a larger case with much more powder, driving bullets about 500 to 700 fps faster than .223 Remington. That gives 22-250 a flatter trajectory and longer effective range. They are not interchangeable.
What is the effective range of 22-250?
In a good rifle, 22-250 is effective on varmints out to about 400 to 500 yards. Its high velocity keeps drop and wind drift low, which makes hitting small targets at long range easier than with most other .22 centerfire cartridges.
More About 22-250 Remington Ammo
22-250 began as a wildcat cartridge in the 1930s, when shooters necked down the .250-3000 Savage case to hold .22 caliber bullets. Known for years as the .22 Varminter, it was one of the most popular wildcats in the country.
Remington made it a factory cartridge in 1965 as the 22-250 Remington, and it quickly became a favorite of varmint hunters and predator callers. It remains one of the best-selling varmint cartridges in North America, offered in rifles from nearly every major manufacturer.